6-(1H-Tetrazol-5-yl)-1H-indole monohydrate
2011
Crystal Structure of 6-(1H-Tetrazol-5-yl)-1H-Indole Monohydrate
publication
Evidence: moderate
Author Information
Author(s): Ge Yu-Hua, Han Pei, Wei Ping, Ou-yang Ping-Kai
Primary Institution: Nanjing University of Technology
Hypothesis
To synthesize indole compounds with tetrazole as a substituent.
Conclusion
The crystal structure of the compound shows a stable arrangement due to hydrogen bonds and π–π interactions.
Supporting Evidence
- The tetrazole ring forms a dihedral angle of 1.82° with the mean plane of the indole fragment.
- Molecules are linked by intermolecular hydrogen bonds into a two-dimensional network.
- Stabilization is provided by weak π–π interactions.
Takeaway
The study looks at a special chemical compound made of indole and tetrazole, which is held together by tiny forces called hydrogen bonds.
Methodology
The compound was synthesized from 6-cyanoindole and characterized using X-ray crystallography.
Digital Object Identifier (DOI)
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