Daily Consumption of Ketone Ester is Safe for Older Adults
Author Information
Author(s): Senadheera Chatura, Blonquist Traci, Stubbs Brianna, Diaz Stephanie Roa, Peralta Sawyer, Stephens Elizabeth, Newman John
Primary Institution: Buck Institute for Research on Aging
Hypothesis
The primary objective of this pilot study was to assess tolerability and safety of ketone ester ingestion in older adults.
Conclusion
The study found that daily consumption of ketone ester is safe and well-tolerated in healthy older adults.
Supporting Evidence
- Participants were randomized to consume either ketone ester or a placebo.
- Tolerability was assessed using a daily log and bi-weekly phone interviews.
- No clinically relevant changes in safety labs or vital signs were observed.
Takeaway
Older adults can safely take a special drink called ketone ester every day without feeling sick.
Methodology
A randomized, placebo-controlled, double-blinded, parallel-arm trial with community-dwelling, independent older adults.
Limitations
The study had a small sample size and a short duration.
Participant Demographics
30 participants (15 males and 15 females) aged 65 to 90 years.
Statistical Information
Confidence Interval
90% CI=2.6–38.5 for KE group; 90% CI=0.4–29.7 for PLA group.
Digital Object Identifier (DOI)
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