Live Bird Markets of Bangladesh: H9N2 Viruses and the Near Absence of Highly Pathogenic H5N1 Influenza
2011

H9N2 Viruses in Live Bird Markets of Bangladesh

Sample size: 5715 publication 10 minutes Evidence: moderate

Author Information

Author(s): Negovetich Nicholas J., Feeroz Mohammed M., Jones-Engel Lisa, Walker David, Alam S. M. Rabiul, Hasan Kamrul, Seiler Patrick, Ferguson Angie, Friedman Kim, Barman Subrata, Franks John, Turner Jasmine, Krauss Scott, Webby Richard J., Webster Robert G.

Primary Institution: St. Jude Children's Research Hospital

Hypothesis

What is the prevalence of H9N2 and H5N1 viruses in the live bird markets of Bangladesh?

Conclusion

The study found a high prevalence of non-pathogenic H9N2 viruses and a very low prevalence of highly pathogenic H5N1 viruses in the live bird markets of Bangladesh.

Supporting Evidence

  • The prevalence of influenza infection in the birds of the live bird markets is 23.0%.
  • Nearly all of the isolates (94%) were of the non-pathogenic H9N2 subtype.
  • The highly pathogenic H5N1-subtype virus was observed at extremely low prevalence in the surveillance samples (0.08%).
  • The current risk of infection for humans in the retail poultry markets in Bangladesh is negligible.

Takeaway

The researchers looked at birds in markets in Bangladesh and found a lot of H9N2 viruses, but very few H5N1 viruses, which means the risk to people is low right now.

Methodology

Active surveillance was conducted by collecting oropharyngeal and cloacal swabs from birds and environmental samples across various locations in Bangladesh.

Potential Biases

Potential bias in sampling methods and reliance on reported outbreaks.

Limitations

The study relied on samples from specific markets and may not represent all areas of Bangladesh.

Participant Demographics

Samples were primarily collected from chickens, with some from ducks and other birds.

Statistical Information

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0019311

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