Blood Sugar Lowering Effect of Coccinia grandis
Author Information
Author(s): M. A. A. K. Munasinghe, C. Abeysena, I. S. Yaddehige, T. Vidanapathirana, P. K. P. B. Piyumal
Primary Institution: General Hospital, Matara, Sri Lanka
Hypothesis
Does Coccinia grandis have a hypoglycemic effect in healthy individuals?
Conclusion
Coccinia grandis has a blood sugar lowering effect.
Supporting Evidence
- Overall blood sugar levels in the experimental group were significantly lower than in the control group.
- The increase in blood sugar levels from fasting to one hour postprandially was statistically significant for the control group.
- The same statistical significance was observed in the two-hour postprandial blood sugar levels.
Takeaway
Eating Coccinia grandis leaves can help lower blood sugar levels after meals.
Methodology
A double-blind phase I clinical trial with 122 healthy volunteers was conducted, comparing Coccinia grandis to a placebo.
Potential Biases
There may be selection bias due to the significant difference in sex between the two groups.
Limitations
The study did not measure BMI or the exact concentration of the active component of Coccinia grandis.
Participant Demographics
Participants were healthy volunteers aged 18-55, with a mix of males and females.
Statistical Information
P-Value
p<0.05
Confidence Interval
95% confidence interval, 4.81 to 35.5 for one hour; 1.03 to 21.9 for two hours.
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website