Senotherapeutics, Aging, and Age-Related Diseases
2024

Senotherapeutics and Aging

publication

Author Information

Author(s): Kellogg Dean

Primary Institution: The University of Texas Health Science Center San Antonio

Hypothesis

Can senotherapeutic agents effectively intervene in aging and age-related diseases?

Conclusion

Senolytic and senomorphic drugs are safe for older individuals and show promise for treating age-related diseases.

Supporting Evidence

  • Numerous pre-clinical trials support the rationale for human clinical trials.
  • New human clinical trials are being proposed to test efficacy in older individuals.

Takeaway

Scientists are testing new medicines that might help older people feel better and live longer.

Methodology

Review of pre-clinical and proposed human clinical trials on senotherapeutic agents.

Participant Demographics

Older persons

Digital Object Identifier (DOI)

10.1093/geroni/igae098.1474

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