First Case of G-CSF-Producing Rectal Cancer
Author Information
Author(s): Takahashi Hiroki, Yasuda Akira, Ochi Nubuo, Sakamoto Masaki, Takayama Satoru, Wakasugi Takehiro, Funahashi Hitoshi, Sawai Hirozumi, Satoh Mikinori, Akamo Yoshimi, Takeyama Hiromitsu
Primary Institution: Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences
Conclusion
This is the first case of G-CSF-producing rectal cancer, and its prognosis was very poor.
Supporting Evidence
- The patient had a white blood cell count that increased significantly after surgery.
- Histopathological examination revealed undifferentiated carcinoma of the rectum.
- The serum level of G-CSF was elevated to 840 pg/mL, indicating G-CSF production by the tumor.
Takeaway
A man had a rare type of rectal cancer that produced a substance called G-CSF, which made his condition worse quickly, and he sadly passed away shortly after surgery.
Methodology
The case involved surgical removal of rectal cancer, followed by histopathological examination and immunohistochemical studies.
Limitations
Only one case is reported, limiting the generalizability of the findings.
Participant Demographics
A 57-year-old man.
Digital Object Identifier (DOI)
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