Septic Shock Patients and Early Goal-Directed Therapy
Author Information
Author(s): Ho Benjamin CH, Bellomo Rinaldo, McGain Forbes, Jones Daryl, Naka Toshio, Wan Li, Braitberg George
Primary Institution: University of Melbourne
Hypothesis
What is the incidence and outcome of septic patients presenting at the emergency department with criteria for early goal-directed therapy?
Conclusion
Candidates for early goal-directed therapy were uncommon, and their mortality was lower than previously reported with such therapy.
Supporting Evidence
- Only 1% of patients with an infectious disease diagnosis were candidates for early goal-directed therapy.
- 70% of candidates for early goal-directed therapy received vasopressor drugs.
- The mortality rate for candidates was 28.8%.
Takeaway
Only a small number of patients with infections needed special treatment called early goal-directed therapy, and they did better than expected without it.
Methodology
This was a retrospective, observational study using electronic databases to identify septic patients admitted to the emergency department over a 3.5-year period.
Potential Biases
Potential for missing patients who could have been candidates for early goal-directed therapy.
Limitations
The study is retrospective and may not apply to other healthcare settings.
Participant Demographics
Adult patients (age >18 years) admitted with infectious conditions.
Statistical Information
P-Value
<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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