Effects of Thai Indigenous Plants on Diabetes in Rats
Author Information
Author(s): Chaiyavat Chaiyasut, Kusirisin Winthana, Lailerd Narissara, Lerttrakarnnon Peerasak, Suttajit Maitree, Srichairatanakool Somdet
Primary Institution: Chiang Mai University
Hypothesis
The study investigates the effects of antioxidant activity from fermented Thai indigenous plants on oxidative stress in diabetic rats.
Conclusion
The fermented product from Thai indigenous plants significantly reduced oxidative stress and slightly improved glucose metabolism in diabetic rats.
Supporting Evidence
- Diabetic rats treated with the fermentation product showed a significant decrease in plasma TBARS levels.
- The higher dose of the fermentation product reduced plasma glucose increase compared to the control group.
- Rats receiving the fermentation product had lower erythrocyte ROS levels.
- Phenolic compounds in the fermentation product were identified as rutin, gallic acid, and pyrogallol.
Takeaway
This study shows that a drink made from certain Thai plants can help diabetic rats feel better by reducing stress in their bodies.
Methodology
Wistar rats with STZ-induced diabetes were treated with a fermentation product of five Thai plants for 6 weeks, and various oxidative stress markers were measured.
Limitations
The study was conducted on rats, and results may not directly translate to humans.
Participant Demographics
Male Wistar rats, aged 180-200g.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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