Study of Placenta in South American Rodents
Author Information
Author(s): Favaron Phelipe O, Carter Anthony M, Ambrósio Carlos E, Morini Adriana C, Mess Andrea M, de Oliveira Moacir F, Miglino Maria A
Primary Institution: University of Sao Paulo
Hypothesis
What is the structure and development of the placenta in Sigmodontinae rodents?
Conclusion
The placenta in Sigmodontinae rodents resembles that of other cricetid rodents, with distinct zones and a hemotrichorial interhemal barrier.
Supporting Evidence
- The chorioallantoic placenta was organized into distinct zones.
- An inverted yolk sac persisted until term.
- The interhemal barrier was hemotrichorial.
- Large numbers of trophoblast giant cells were observed.
- Glycogen cells invaded the decidua.
Takeaway
This study looks at how the placenta works in certain South American rodents, showing that it has some similarities to other rodents.
Methodology
Placentas from five genera were studied using histology, immunohistochemistry, and transmission electron microscopy.
Limitations
The study was based on wild-trapped specimens, which may not provide a complete understanding of placentation across gestational ages.
Digital Object Identifier (DOI)
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