Non-Targeted Metabolomics Analysis Reveals Metabolite Profiles Change During Whey Fermentation with Kluyveromyces marxianus
2024

Changes in Metabolite Profiles During Whey Fermentation

Sample size: 6 publication Evidence: high

Author Information

Author(s): Gao Yansong, Gao Lei, Kang You, Yang Ge, Zhao Zijian, Zhao Yujuan, Li Shengyu

Primary Institution: Institute of Agro-Food Technology, Jilin Academy of Agricultural Sciences

Hypothesis

How does the fermentation of whey by Kluyveromyces marxianus affect its metabolite profiles over time?

Conclusion

Fermentation with KM812 significantly enhances the nutritional and functional properties of whey by increasing the levels of beneficial metabolites.

Supporting Evidence

  • A total of 151 differential metabolites were identified during the fermentation process.
  • The highest relative content of whey metabolites was observed at 48 hours of fermentation.
  • Fermentation significantly increased levels of amino acids, fatty acids, and carbohydrates.
  • KEGG analysis revealed associations with 23 specific metabolites and 9 metabolic pathways.

Takeaway

When we let a special yeast ferment whey, it makes the whey healthier by creating more good stuff in it over time.

Methodology

A non-targeted metabolomics approach using liquid chromatography–mass spectrometry (LC-MS) was employed to analyze changes in whey metabolites during fermentation.

Limitations

The initial metabolic profiles do not fully elucidate the mechanisms underlying the synthesis or degradation of different metabolites.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/metabo14120694

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication