Inflammatory and Nutritional Indices in Postmenopausal Osteoporosis
Author Information
Author(s): Busra Demir Cendek, Burak Bayraktar, Mehmet Alican Sapmaz, Ayse Ecenaz Yıldırım, Mujde Can Ibanoglu, Yaprak Engin Ustun, Johannes Ott
Primary Institution: Health Sciences University Etlik Zubeyde Hanim Maternity, Teaching and Research Hospital, Ankara, Turkey
Hypothesis
This study aimed to evaluate the potential of inflammatory and nutritional markers in identifying decreased bone mineral density (BMD) in postmenopausal women.
Conclusion
The findings suggest that the GNRI could serve as a useful indicator for assessing bone health and the risk of osteoporosis.
Supporting Evidence
- The GNRI was significantly lower in the osteoporosis group compared to the control group.
- Magnesium levels were lower in the osteoporosis group than in the control and osteopenia groups.
- The Na/Mg ratio was higher in the osteoporosis group compared to the control group.
- The Ca/Mg ratio was lower in the osteoporosis group than in the control group.
- The T-score was positively correlated with magnesium and Ca/Mg ratios.
Takeaway
This study found that certain nutritional scores can help identify women at risk for osteoporosis, and keeping magnesium levels balanced is important for bone health.
Methodology
This cross-sectional study retrospectively analyzed medical records of postmenopausal women from January 2018 to December 2023.
Potential Biases
Potential bias due to the retrospective nature of the study and exclusion of certain health conditions.
Limitations
The study's data collection was limited to a single time point, and factors like alcohol and tobacco consumption were not recorded.
Participant Demographics
Postmenopausal women aged 55-61, with varying degrees of bone mineral density.
Statistical Information
P-Value
0.013
Confidence Interval
95% CI: 0.597–0.752
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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