Demographic and microbial characteristics of extrapulmonary tuberculosis cases diagnosed in Malatya, Turkey, 2001-2007
2011

Characteristics of Extrapulmonary Tuberculosis in Malatya, Turkey

Sample size: 397 publication 10 minutes Evidence: moderate

Author Information

Author(s): Gunal Selami, Yang Zhenhua, Agarwal Mansi, Koroglu Mehmet, Arıcı Zeynep Kazgan, Durmaz Riza

Primary Institution: Inonu University, Malatya, Turkey

Hypothesis

What are the demographic and microbial characteristics of extrapulmonary tuberculosis (EPTB) cases in Malatya, Turkey?

Conclusion

Extrapulmonary tuberculosis accounted for a significant proportion of tuberculosis cases in Malatya, Turkey, between 2001 and 2007.

Supporting Evidence

  • 103 out of 397 TB patients had extrapulmonary tuberculosis (EPTB).
  • The most common types of EPTB were genitourinary TB (27.2%) and meningeal TB (19.4%).
  • Patients older than 45 years had an increased risk of EPTB.

Takeaway

This study looked at people with a type of tuberculosis that affects parts of the body other than the lungs, finding that many cases were in older adults and that different types of this disease were more common in men and women.

Methodology

The study evaluated clinical and laboratory data of 397 bacteriologically-confirmed TB cases diagnosed over eight years using chi-square analysis and multivariate logistic regression.

Potential Biases

The small sample size may limit the statistical power to detect associations.

Limitations

The study did not assess concurrent pulmonary and extrapulmonary involvement due to lack of information about additional disease sites.

Participant Demographics

Of the 397 patients, 238 (59.9%) were males and 159 (40.1%) were females, with a median age of 32 years.

Statistical Information

P-Value

0.03

Confidence Interval

95% CI [1.59, 5.00]

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1186/1471-2458-11-154

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