Perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care (LAFA trial)
2006

LAFA Trial: Comparing Laparoscopic Surgery and Fast Track Care in Colonic Surgery

Sample size: 400 publication 10 minutes Evidence: moderate

Author Information

Author(s): Jan Wind, Jan Hofland, Benedikt Preckel, Markus W Hollmann, Patrick MM Bossuyt, Dirk J Gouma, Mark I van Berge Henegouwen, Jan Willem Fuhring, Cornelis HC Dejong, Ronald M van Dam, Miguel A Cuesta, Astrid Noordhuis, Dick de Jong, Edith van Zalingen, Alexander F Engel, T Hauwy Goei, Erica I de Stoppelaar, Willem F van Tets, Bart A van Wagensveld, Annemiek Swart, Maarten JLJ van den Elsen, Michael F Gerhards, Laurens Th de Wit, Muriel AM Siepel, Anna AW van Geloven, Jan-Willem Juttmann, Wilfred Clevers, Willem A Bemelman

Primary Institution: Academic Medical Center Amsterdam

Hypothesis

Is laparoscopic surgery with fast track care better than open surgery with standard care for segmental colectomy in malignant disease?

Conclusion

The LAFA trial aims to determine the best approach for segmental colectomy, focusing on recovery time and quality of life.

Supporting Evidence

  • Laparoscopic surgery has been shown to reduce postoperative pain and recovery time.
  • Fast track programs can enable patients to leave the hospital as early as three days after surgery.
  • The study aims to compare the effectiveness of laparoscopic surgery and fast track care against traditional methods.

Takeaway

This study is trying to find out if using a special fast track recovery program and laparoscopic surgery helps patients recover faster than traditional methods.

Methodology

The study is a double-blinded, multicenter, randomized controlled trial with a 2x2 factorial design.

Potential Biases

Potential bias in nursing care based on experience with fast track programs.

Limitations

The study may face challenges in implementation due to traditional practices in surgery.

Participant Demographics

Patients aged 40-80 with colorectal cancer, ASA I-III.

Statistical Information

P-Value

0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2482-6-16

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