Comparison of the effect of albumin with platelet-rich fibrin (Alb-PRF) gel and hyaluronic acid gel injection on interdental papilla reconstruction: A randomized clinical trial
2024

Comparing Albumin with Platelet-Rich Fibrin Gel and Hyaluronic Acid for Papilla Reconstruction

Sample size: 46 publication 10 minutes Evidence: moderate

Author Information

Author(s): Vadiati Saberi, Khalighi Sigaroudi, Kamani Mobina, Rafiei Elahe

Primary Institution: Guilan University of Medical Sciences

Hypothesis

Does the injection of albumin with platelet-rich fibrin gel (Alb-PRF) provide better results than hyaluronic acid gel for interdental papilla reconstruction?

Conclusion

Both HA and Alb-PRF injections can significantly reduce the area of black triangles in interdental papillae, leading to patient satisfaction.

Supporting Evidence

  • Both treatment groups showed significant reduction in black triangle areas over time.
  • Patient satisfaction scores were similar between both treatment groups.
  • No significant differences in plaque index were observed between the two groups.

Takeaway

Doctors tested two types of gels to help fix gaps in gums between teeth, and both worked pretty well.

Methodology

46 patients with incomplete interdental papillae were randomly assigned to receive either Alb-PRF or HA gel injections at 21-day intervals, with evaluations at 3 and 6 months.

Potential Biases

Potential selection bias due to the exclusion criteria and small sample size.

Limitations

The study had a small sample size and was limited to a specific age range.

Participant Demographics

10 volunteers aged 20-75, with a mean age of 41.24 years, including 6 men and 4 women.

Statistical Information

P-Value

p=0.994

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.34172/japid.2024.018

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