ProFace: A Server for Analyzing Protein-Protein Interfaces
Author Information
Author(s): Saha Rudra P, Bahadur Ranjit P, Pal Arumay, Mandal Saptarshi, Chakrabarti Pinak
Primary Institution: Bose Institute
Hypothesis
Understanding the physicochemical features of protein-protein interfaces can enhance our knowledge of protein interactions and aid in designing molecules to control protein function.
Conclusion
ProFace is a web-server developed to analyze protein-protein interfaces and derive various physicochemical parameters.
Supporting Evidence
- ProFace can dissect a protein-protein interface and derive physicochemical parameters.
- The output can be used to display the interface with standard software.
- Understanding the biological significance of protein interactions is enhanced through this analysis.
Takeaway
ProFace is a tool that helps scientists understand how proteins interact with each other by analyzing their surfaces.
Methodology
ProFace analyzes the interface between protein subunits using input files in PDB format and provides various output files detailing interface parameters.
Digital Object Identifier (DOI)
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