SARS-CoV-2 Infections in a Triad of Primary School Learners (Grades 1-7), Their Parents, and Teachers in KwaZulu-Natal, South Africa: Protocol for a Cross-Sectional and Nested Case-Cohort Study
2024

SARS-CoV-2 Infections in Primary School Learners, Parents, and Teachers in South Africa

Sample size: 640 publication Evidence: moderate

Author Information

Author(s): Leung Tiffany, Gornyk Daniela, Dassaye Reshmi, Chetty Terusha, Daniels Brodie, Gaffoor Zakir, Spooner Elizabeth, Ramraj Trisha, Mthethwa Ncengani, Nsibande Duduzile Faith, Pillay Saresha, Bhana Arvin, Magasana Vuyolwethu, Reddy Tarylee, Mohlabi Khanya, Moore Penelope Linda, Burgers Wendy A, de Oliveira Tulio, Msomi Nokukhanya, Goga Ameena

Primary Institution: South African Medical Research Council

Hypothesis

What is the prevalence of SARS-CoV-2 infections and related health impacts among primary school learners, their parents, and teachers in KwaZulu-Natal, South Africa?

Conclusion

The study aims to provide important data on SARS-CoV-2 infections and their effects on school-attending children, parents, and teachers in South Africa.

Supporting Evidence

  • Approximately 75.3 million children and adolescents globally have tested positive for COVID-19.
  • In South Africa, children aged <20 years make up a significant portion of the population.
  • Previous studies have shown varying seroprevalence rates among children and adults during the pandemic.

Takeaway

This study is looking at how many kids, their parents, and teachers have had COVID-19 and how it affects their health.

Methodology

The study includes a cross-sectional survey, a follow-up survey, and a nested case-cohort substudy involving blood and saliva sample collection.

Potential Biases

Potential oversampling or undersampling at schools due to recruitment challenges.

Limitations

Findings may not be representative of all South African schools due to the limited geographic area and number of schools involved.

Participant Demographics

Participants include primary school learners (grades 1-7), their parents, and teachers from KwaZulu-Natal.

Digital Object Identifier (DOI)

10.2196/52713

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