Nationwide trends in molecular epidemiology of methicillin-resistant Staphylococcus aureus, Finland, 1997–2004
2007

Trends in MRSA in Finland (1997–2004)

Sample size: 4091 publication Evidence: moderate

Author Information

Author(s): Kerttula Anne-Marie, Lyytikäinen Outi, Kardén-Lilja Minna, Ibrahem Salha, Salmenlinna Saara, Virolainen Anni, Vuopio-Varkila Jaana

Primary Institution: National Public Health Institute, Helsinki, Finland

Hypothesis

What are the trends in molecular epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) in Finland from 1997 to 2004?

Conclusion

The predominant MRSA strains change over time, indicating a need for ongoing control measures.

Supporting Evidence

  • MRSA notifications rose from 120 in 1997 to 1458 in 2004.
  • The proportion of MRSA among S. aureus blood isolates tripled from <1% to 2.8% during the study period.
  • 253 different strains were identified among 4091 MRSA isolates.

Takeaway

The number of MRSA cases in Finland increased significantly from 1997 to 2004, showing that some strains are becoming more common.

Methodology

Data on MRSA notifications were analyzed, and isolates were characterized using PFGE, MLST, and SCCmec typing.

Limitations

The study could not assess health-care records or differentiate between clinical and screening specimens over the entire period.

Participant Demographics

The study included MRSA notifications from various hospital districts in Finland, covering a population of 5.2 million.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2334-7-94

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