Changes in body weight, body composition and cardiovascular risk factors after long-term nutritional intervention in patients with severe mental illness: an observational study
2011

Nutritional Intervention for Weight Loss in Patients with Severe Mental Illness

Sample size: 989 publication Evidence: moderate

Author Information

Author(s): Hassapidou Maria, Papadimitriou Konstantina, Athanasiadou Niki, Tokmakidou Valasia, Pagkalos Ioannis, Vlahavas George, Tsofliou Fotini

Primary Institution: Department of Nutrition and Dietetics, School of Food Technology and Nutrition, Technological Educational Institute of Thessaloniki, Greece

Hypothesis

The study aimed to investigate the effects of a long-term nutritional intervention on body weight, body fat, and cardiovascular risk factors in patients with severe mental illness.

Conclusion

The nutritional intervention produced significant reductions in body weight, body fat, and improved the cardiometabolic profile in patients with severe mental illness.

Supporting Evidence

  • The mean final weight loss was 9.7 kg and BMI decreased to 30.7 kg/m2.
  • There were significant reductions in fasting plasma glucose, total cholesterol, and triglycerides concentrations throughout the study.
  • The intervention included personalized dietary counseling based on a Mediterranean-style diet.

Takeaway

This study shows that helping people with severe mental illness eat better can help them lose weight and be healthier.

Methodology

The study involved a 9-month nutritional intervention with personalized dietetic treatment and lifestyle counseling for 989 patients, with measurements taken at baseline, 3 months, 6 months, and 9 months.

Potential Biases

Psychiatric disorders may have influenced participants' ability to adhere to the weight loss program.

Limitations

The study did not include a control group, and there was a significant drop-out rate among participants.

Participant Demographics

The sample included 774 women and 215 men, with a mean age of 40 years.

Statistical Information

P-Value

p < 0.001

Statistical Significance

p < 0.001

Digital Object Identifier (DOI)

10.1186/1471-244X-11-31

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