Developing and testing a toolkit of interventions to improve adherence to non-invasive ventilation in children: the SPIRITUS study protocol
2024

Improving Non-Invasive Ventilation Adherence in Children

Sample size: 10 publication Evidence: moderate

Author Information

Author(s): Russell Jessica, Chan Elaine Y, Davies Gwyneth, Gibson Faith, Harniess Philip, Rendle Garry, Wray Jo

Primary Institution: Great Ormond Street Hospital for Children NHS Foundation Trust

Hypothesis

What interventions exist to address adherence to NIV in children and young people?

Conclusion

The study aims to develop a toolkit of interventions to improve adherence to non-invasive ventilation in children with sleep disordered breathing.

Supporting Evidence

  • Non-invasive ventilation is effective for children with sleep disordered breathing.
  • Poor adherence to NIV can lead to undertreatment of sleep disordered breathing.
  • Adherence to NIV is often suboptimal, with many children at risk of adverse health outcomes.

Takeaway

This study is trying to find better ways to help kids use their breathing machines so they can sleep better and be healthier.

Methodology

A mixed methods study over three phases to identify and test interventions for improving NIV adherence.

Potential Biases

Selection bias may occur as parents must consent for their child's participation.

Limitations

The study is single-site, which may limit the generalizability of the results.

Participant Demographics

Children aged 0-18 years with sleep disordered breathing who have been prescribed NIV.

Digital Object Identifier (DOI)

10.1136/bmjopen-2024-090570

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