Latent Portal Hypertension in Benign Biliary Obstruction

Sample size: 20 publication Evidence: moderate

Author Information

Author(s): MD. IBRARULLAH, S. S. SIKORA, D. K. AGARWAL, V. K. KAPOOR, S. P. KAUSHIK

Primary Institution: Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

Does benign biliary obstruction lead to changes in portal venous pressure without overt clinical manifestations of portal hypertension?

Benign biliary obstruction can lead to elevated portal pressure even without clinical signs of portal hypertension.

Portal venous pressure was found to be elevated in 7 out of 20 patients.
The mean fall of portal venous pressure was 3.4 cm of saline after biliary decompression.
No correlation was found between portal venous pressure and duration of biliary obstruction.
Liver histology showed mild to moderate cholestatic changes but maintained portal architecture.

Some people with blocked bile ducts can have high pressure in their blood vessels, even if they don't show any symptoms.

Portal venous pressure was measured in 20 patients with benign biliary obstruction before and after biliary decompression.

The study did not measure the portal pressure gradient, which may affect the interpretation of results.

9 males and 11 females, mean age 38 years.

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