Fungal Cytochrome P450 Database
Author Information
Author(s): Park Jongsun, Lee Seungmin, Choi Jaeyoung, Ahn Kyohun, Park Bongsoo, Park Jaejin, Kang Seogchan, Lee Yong-Hwan
Primary Institution: Seoul National University
Hypothesis
An efficient bioinformatics platform specialized for cytochrome P450 enzymes in fungi is highly desirable.
Conclusion
The Fungal Cytochrome P450 Database (FCPD) will facilitate systematic identification and multifaceted analyses of P450s at multiple taxon levels via the web.
Supporting Evidence
- The FCPD archives 4,538 P450 genes from 66 fungal and 4 oomycete species.
- P450s were classified into 16 classes based on InterPro terms.
- The proportion of P450s in the total proteome exhibited taxon-specific characteristics.
Takeaway
Scientists created a special online database to help study important proteins in fungi that help them adapt to their environments.
Methodology
The FCPD archives genes encoding P450s in the genomes of 66 fungal and 4 oomycete species and supports analyses of their sequences and evolutionary histories.
Limitations
The automated annotation process may result in some false positives and negatives.
Digital Object Identifier (DOI)
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