Complications of Mesenteric Vein Thrombosis: Heterozygous Factor V Leiden Mutation Leads to Pulmonary Embolism in a Patient With Post–Bowel Resection Surgery
2025

Pulmonary Embolism After Bowel Surgery Due to Factor V Leiden Mutation

Sample size: 1 publication Evidence: low

Author Information

Author(s): Hamza Hafiz Muhammad, Malik Muhammad Muiz, Awan Ayaz Ahmed, Tariq Muhammad Daoud, Daoud Mohamed, Goyal Aman

Hypothesis

Is the Factor V Leiden mutation a significant risk factor for pulmonary embolism in patients with gastrointestinal issues post-surgery?

Conclusion

The presence of the Factor V Leiden mutation highlights the need for thorough thrombophilia assessments in patients with gastrointestinal problems and postoperative complications.

Supporting Evidence

  • The patient had a history of bowel resection surgery and presented with acute breathlessness.
  • Laboratory tests confirmed the presence of a heterozygous Factor V Leiden mutation.
  • The patient was treated with rivaroxaban, which stabilized his condition.

Takeaway

A man had a blood clot in his lungs after surgery, and doctors found he had a special gene that made him more likely to get clots. They treated him with medicine to help his blood flow better.

Methodology

The patient underwent a thorough clinical examination, laboratory investigations, and imaging studies including computed tomography pulmonary angiography (CTPA).

Limitations

The study is based on a single case report, limiting the generalizability of the findings.

Participant Demographics

A 60-year-old Asian male.

Digital Object Identifier (DOI)

10.1002/ccr3.70092

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