In Utero Diagnosis of Agenesis of the Ductus Arteriosus in a Twin Pregnancy
Author Information
Author(s): Kecia Gaither, Andrea Ardite, Sarita Dhuper
Primary Institution: Brookdale University Hospital and Medical Center
Hypothesis
Isolated premature closure of the ductus with or without congenital heart disease can result in right sided heart failure and fetal hypoxemia resulting in hydrops fetalis.
Conclusion
The study highlights the association of Tetralogy of Fallot and absent or premature closure of the ductus arteriosus, which should be considered during prenatal evaluations.
Supporting Evidence
- Both twins presented with congenital heart defects and absent ductus arteriosus.
- Twin B exhibited signs of hydrops and required urgent delivery.
- Both infants had progressive cyanosis and failed to improve with treatment.
Takeaway
This study talks about two babies in a twin pregnancy who had heart problems because a part of their heart called the ductus arteriosus was missing, which made them very sick.
Methodology
Case report detailing prenatal diagnosis and outcomes of two twins with congenital heart defects.
Limitations
The parents declined autopsy for Twin A, limiting further understanding of the condition.
Participant Demographics
34-year-old African American woman, Gravida-4, Para-3.
Digital Object Identifier (DOI)
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