Prevalence and Risk Factors of Osteoporosis in Postmenopausal Women
Author Information
Author(s): Özmen Samican, Kurt Sefa, Timur Hikmet Tunç, Yavuz Onur, Kula Hakan, Demir Ayşegül Yılmaz, Balcı Ali
Primary Institution: Dokuz Eylul University, Department of Obstetrics and Gynecology
Hypothesis
This study aimed to evaluate the prevalence and risk factors for osteoporosis among postmenopausal women using a 10-year dataset.
Conclusion
The study found that smoking, diabetes, and a history of fractures significantly increase the risk of osteoporosis, while higher BMI has a protective effect.
Supporting Evidence
- The prevalence of osteoporosis was found to be 10.4%.
- Smoking increased the risk of osteoporosis by 2.46 times.
- Diabetes increased the risk of osteoporosis by 3.78 times.
- A history of fractures increased the risk of osteoporosis by 6.23 times.
- Higher BMI was found to have a protective effect against osteoporosis.
Takeaway
Osteoporosis is a disease that makes bones weak and more likely to break, especially in older women. Things like smoking and having diabetes can make it worse, but being a healthy weight can help protect against it.
Methodology
This retrospective cohort study analyzed data from 3289 postmenopausal women aged 50-60 who underwent routine gynecological checkups and DXA scans from 2010 to 2022.
Potential Biases
Potential bias due to reliance on verbal anamnesis for fracture history and exclusion of certain demographics.
Limitations
The study was conducted in a single center and may not represent the broader population; it also relied on self-reported history of fractures.
Participant Demographics
Postmenopausal women aged 50-60 years, with a median age of 56.0 years.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI: 1.92–3.15 for smoking, 95% CI: 2.89–4.93 for diabetes, 95% CI: 4.79–8.08 for history of fractures.
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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