The correlation between endometrial thickness and outcome of in vitro fertilization and embryo transfer (IVF-ET) outcome
2008

Endometrial Thickness and IVF Success

Sample size: 2464 publication Evidence: moderate

Author Information

Author(s): Al-Ghamdi Ahlam, Coskun Serdar, Al-Hassan Saad, Al-Rejjal Rafat, Awartani Khalid

Primary Institution: King Faisal Specialist Hospital and Research Centre

Hypothesis

Is there a relationship between endometrial thickness on the day of hCG administration and pregnancy outcomes in IVF cycles?

Conclusion

A thicker endometrium is associated with higher pregnancy rates in IVF cycles.

Supporting Evidence

  • Pregnancy rates increased from 29.4% with ≤6 mm endometrial thickness to 44.4% with ≥17 mm.
  • The study analyzed a total of 2464 IVF cycles.
  • Endometrial thickness was measured on the day of hCG administration.

Takeaway

If the lining of the uterus is thicker, it can help women get pregnant during IVF treatments.

Methodology

A retrospective cohort study analyzing IVF cycles from January 2003 to December 2005.

Potential Biases

Potential bias due to the retrospective nature of the study.

Limitations

The study is retrospective and may not account for all variables affecting pregnancy outcomes.

Participant Demographics

Patients undergoing IVF at a tertiary center, with a mean age of approximately 30 years.

Statistical Information

P-Value

p=0.001

Confidence Interval

95% CI 1.12–1.41

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1186/1477-7827-6-37

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