Breast cancer risk and drinking water contaminated by wastewater: a case control study
2006

Breast Cancer Risk and Contaminated Drinking Water

Sample size: 1569 publication Evidence: low

Author Information

Author(s): Julia Green Brody, Ann Aschengrau, Wendy McKelvey, Christopher H Swartz, Theresa Kennedy, Ruthann A Rudel

Primary Institution: Silent Spring Institute

Hypothesis

Does exposure to drinking water contaminated by wastewater increase the risk of breast cancer?

Conclusion

The study found no evidence of an association between breast cancer and drinking water contaminated by wastewater.

Supporting Evidence

  • Results showed no consistent association between breast cancer and average annual nitrate-N levels.
  • 99% of women received water from supplies with nitrate-N levels above background.
  • Odds ratios for nitrate-N exposure were not significantly elevated.

Takeaway

The study looked at whether drinking water contaminated with wastewater could cause breast cancer, but it didn't find any proof that it does.

Methodology

A case-control study involving 824 breast cancer cases and 745 controls, assessing exposure to nitrate nitrogen levels in drinking water.

Potential Biases

Potential for non-differential misclassification of exposure due to limited data on individual behaviors.

Limitations

Limited exposure variation and reliance on historical data may affect the results.

Participant Demographics

Predominantly white women aged 60 to 80 with a high school education or higher.

Statistical Information

Confidence Interval

95% CI 0.5 – 5.0 for nitrate-N levels

Digital Object Identifier (DOI)

10.1186/1476-069X-5-28

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