Study of Cissampelos mucronata and Tephrosia villosa for Larvicidal and Antimicrobial Properties
Author Information
Author(s): O Nondo Ramadhani, Mbwambo Zakaria H, Kidukuli Abdul W, Innocent Ester M, Mihale Matobola J, Erasto Paul, Moshi Mainen J
Primary Institution: Muhimbili University of Health and Allied Sciences (MUHAS)
Hypothesis
The extracts from Cissampelos mucronata and Tephrosia villosa have potential larvicidal and antimicrobial activities.
Conclusion
The study found that C. mucronata has potential antimicrobial and larvicidal properties, while T. villosa is toxic to brine shrimp and may yield cytotoxic compounds.
Supporting Evidence
- C. mucronata extracts showed antibacterial activity against several pathogens.
- T. villosa extracts were highly toxic to brine shrimp.
- C. mucronata root extracts exhibited good larvicidal activity.
- Ethanolic extracts from T. villosa fruits and roots were very toxic.
Takeaway
This study looked at two plants to see if they could help kill mosquito larvae and fight germs. One plant worked well, while the other was found to be very toxic.
Methodology
The study used extracts from the roots and aerial parts of C. mucronata and T. villosa, testing them for larvicidal activity on mosquito larvae, brine shrimp toxicity, and antimicrobial activity against various bacteria and fungi.
Limitations
The study did not explore the specific bioactive compounds responsible for the observed effects.
Digital Object Identifier (DOI)
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