IMPROVING OUTCOMES IN OLDER VETERANS WITH HEART FAILURE AND CKD: FROM PROPENSITY SCORE USE TO AI
2024

Improving Outcomes in Older Veterans with Heart Failure and CKD

publication Evidence: high

Author Information

Author(s): Ahmed Ali

Primary Institution: Washington DC Veterans Medical Center

Hypothesis

Can high-dose renin-angiotensin system inhibitors improve outcomes in older patients with heart failure and chronic kidney disease?

Conclusion

High-dose renin-angiotensin system inhibitors lower the risk of kidney failure and death in octogenarians with heart failure and chronic kidney disease.

Supporting Evidence

  • Renin-angiotensin system inhibitors improve outcomes in patients with heart failure and chronic kidney disease.
  • High-dose RASIs lower risk of kidney failure and death in octogenarians with heart failure and CKD.
  • Artificial intelligence methods can personalize care for older patients.

Takeaway

Older veterans with heart problems and kidney issues can benefit from certain medications, which can help them live longer and healthier.

Methodology

Outcome-blinded propensity score matched studies.

Limitations

Older adults are often excluded from randomized controlled trials, leading to a lack of RCT evidence.

Participant Demographics

Older patients, specifically octogenarians.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0938

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