Yeast Postbiotics Help Young Pigs Fight E. coli Infections
Author Information
Author(s): Gormley Alexa R., Duarte Marcos Elias, Deng Zixiao, Kim Sung Woo
Primary Institution: North Carolina State University
Hypothesis
Saccharomyces yeast postbiotics could enhance the microbiota and mucosal immune response in the jejunum, mitigating the effects of infection with enterotoxigenic E. coli.
Conclusion
Saccharomyces yeast postbiotics could reduce the negative effects associated with F18+ E. coli infection in young pigs.
Supporting Evidence
- SYP improved fecal scores compared to the positive control group.
- SYP reduced protein carbonyl levels, indicating lower oxidative stress.
- SYP increased gene expression of mTOR, which is associated with cell growth and repair.
- Challenge with F18+ E. coli negatively impacted growth performance in pigs.
Takeaway
This study found that a special yeast can help baby pigs stay healthy and not get sick from a bad germ that causes diarrhea.
Methodology
Thirty-six nursery pigs were divided into three groups: a negative control, a positive control challenged with E. coli, and a group receiving Saccharomyces yeast postbiotics, with various health parameters measured after a 28-day period.
Potential Biases
Potential bias in treatment allocation and environmental factors affecting pig health were not fully controlled.
Limitations
The study was limited to a specific strain of E. coli and a controlled environment, which may not fully represent field conditions.
Participant Demographics
The study involved 36 nursery pigs, consisting of 18 barrows and 18 gilts, weaned at 21 days of age.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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