Echocardiographic Assessment of Heart Function in Babies of Diabetic Mothers
Author Information
Author(s): Sonaglioni Andrea, Bruno Antonino, Nicolosi Gian Luigi, Bianchi Stefano, Lombardo Michele, Muti Paola
Primary Institution: IRCCS MultiMedica
Hypothesis
The study aims to examine the impact of gestational diabetes mellitus (GDM) on the heart function of fetuses and infants.
Conclusion
Gestational diabetes is linked to impaired heart function in fetuses and infants of diabetic mothers.
Supporting Evidence
- GDM is associated with significant reductions in left and right ventricular global longitudinal strain.
- Substantial heterogeneity was detected in the studies assessing the impact of GDM on heart function.
- Early detection of myocardial dysfunction in infants of diabetic mothers can be achieved through advanced echocardiographic techniques.
Takeaway
Moms with diabetes can affect their babies' hearts, making them work differently even before they are born.
Methodology
The study analyzed echocardiographic data from 18 studies comparing heart function in fetuses and infants of mothers with and without gestational diabetes.
Potential Biases
Potential biases due to the exclusion of studies on pre-gestational diabetes and limited follow-up data.
Limitations
The review included a small number of heterogeneous studies with limited sample sizes and did not assess postpartum cardiac function in most cases.
Participant Demographics
The studies included a mix of fetuses and infants, with a majority being White and Asian ethnicities.
Statistical Information
P-Value
p < 0.001
Confidence Interval
95%CI −1.23, −0.60
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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