Environmentally Adapted Campylobacter in the UK
Author Information
Author(s): Sopwith Will, Birtles Andrew, Matthews Margaret, Fox Andrew, Gee Steven, Painter Michael, Regan Martyn, Syed Qutub, Bolton Eric
Primary Institution: Health Protection Agency (North West), Liverpool, UK
Hypothesis
What factors drive the early summer increase of Campylobacter cases in the UK?
Conclusion
The study found that the Campylobacter strain ST-45 is strongly associated with early summer peaks in human infections and is frequently isolated from surface waters.
Supporting Evidence
- ST-45 was the third most prevalent sequence type reported in the study.
- Seventy-four river water samples were positive for C. jejuni, with ST-45 being the most prevalent.
- Cases of ST-45 were more likely to be reported in early summer than during the rest of the year.
- Consumption of chicken was less associated with ST-45 infection compared to other types.
- Children under 5 years of age were significantly more likely to be infected with ST-45.
Takeaway
Scientists found a type of bacteria called Campylobacter that likes to live in water and makes people sick, especially in the summer.
Methodology
The study analyzed human cases of Campylobacter infection and collected water samples from rivers to identify the presence of different Campylobacter strains.
Potential Biases
Potential bias due to low reported exposures to water and unrecorded dog exposures.
Limitations
Data on exposure variables were not available for all cases, which reduced statistical power.
Participant Demographics
The study included human cases of Campylobacter infection in northwestern England, with a notable association for children under 5 years old.
Statistical Information
P-Value
0.001
Confidence Interval
1.56–4.99
Statistical Significance
p=0.001
Digital Object Identifier (DOI)
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