The Impact of Preoperative Hip Heterotopic Ossification Extent on Recurrence in Patients with Head and Spinal Cord Injury: A Case Control Study
2011

Impact of Hip Heterotopic Ossification on Recurrence After Surgery

Sample size: 95 publication 10 minutes Evidence: moderate

Author Information

Author(s): Genêt François, Jourdan Claire, Lautridou Christine, Chehensse Clément, Minooee Kambiz, Denormandie Philippe, Schnitzler Alexis

Primary Institution: CHU R.Poincaré, Garches, France

Hypothesis

Is there a relationship between the recurrence risk after hip heterotopic ossification excision and the preoperative extent of heterotopic ossification in patients with traumatic brain injury and spinal cord injury?

Conclusion

No significant relationship was found between the preoperative extent of troublesome hip heterotopic ossification and the risk of recurrence after surgical excision.

Supporting Evidence

  • The study included 19 cases of recurrence and 76 controls matched by sex, pathology, and age.
  • No significant link was found between recurrence and operative delay or the preoperative extent of heterotopic ossification.
  • The median delay for first surgery was significantly longer in the recurrence group compared to controls.

Takeaway

The study looked at patients who had surgery for bone growth around the hip and found that how much bone had grown before surgery didn't help predict if it would grow back again.

Methodology

A case control study comparing TBI and SCI patients who underwent surgery for troublesome hip heterotopic ossification, with 19 cases of recurrence and 76 controls matched by sex, pathology, and age.

Potential Biases

The sample included only patients with severe cases of heterotopic ossification, which may not represent the general population.

Limitations

The study may lack power for separate analysis of TBI and SCI due to small sample sizes and potential selection bias.

Participant Demographics

The study included 95 patients (85 men, median age 30.2 years) with traumatic brain injury and spinal cord injury.

Statistical Information

P-Value

p=0.51

Confidence Interval

95% CI: 0.47–5.19

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0023129

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