Ginsenoside-Rg1 Protects the Liver from Exercise-Induced Damage
Author Information
Author(s): Korivi Mallikarjuna, Hou Chien-Wen, Huang Chih-Yang, Lee Shin-Da, Hsu Ming-Fen, Yu Szu-Hsien, Chen Chung-Yu, Liu Yung-Yang, Kuo Chia-Hua
Primary Institution: Taipei Physical Education College
Hypothesis
Can ginsenoside-Rg1 protect the liver against oxidative damage caused by exhaustive exercise?
Conclusion
Ginsenoside-Rg1 significantly reduces oxidative stress in the liver caused by exhaustive exercise in rats.
Supporting Evidence
- Ginsenoside-Rg1 reduced oxidative damage markers in the liver after exhaustive exercise.
- Liver antioxidant enzyme activities were maintained in ginsenoside-Rg1 pretreated rats.
- Ginsenoside-Rg1 prevented the decrease in glutathione levels after exercise.
Takeaway
This study shows that a substance from ginseng can help protect the liver from damage when rats exercise a lot.
Methodology
Rats were divided into two groups, one receiving ginsenoside-Rg1 and the other a vehicle, and then subjected to exhaustive swimming after 10 weeks of treatment.
Limitations
The study was conducted on rats, and results may not directly translate to humans.
Participant Demographics
Healthy male Sprague Dawley rats, aged 4 months.
Statistical Information
P-Value
p<0.01
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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