The Effect of Frailty on Cognition in Older Adults
Author Information
Author(s): Yuan Yiyang, Lapane Kate
Primary Institution: University of Massachusetts Chan Medical School
Hypothesis
This study aims to examine the effect of physical frailty on cognitive function with depressive symptoms as a mediator in older adults.
Conclusion
Physical frailty decreases cognitive function, but the effects may not be clinically meaningful due to the short follow-up period.
Supporting Evidence
- Physical frailty was measured using the Fried frailty phenotype.
- Depressive symptoms were assessed using the Center for Epidemiological Studies Depression Scale.
- Cognitive function was measured using the Mini-Mental State Examination.
Takeaway
Being physically frail can make it harder for older people to think clearly, and feeling sad can make this even worse.
Methodology
Causal mediation analysis was used to assess the effects of physical frailty and depressive symptoms on cognitive function.
Limitations
The lack of clinically meaningful effects is likely due to the short length of follow-up.
Participant Demographics
Adults aged 65 and above in the United States.
Statistical Information
Confidence Interval
95% CI: -0.59 to 0.07
Digital Object Identifier (DOI)
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