Antibacterial Household Products: Cause for Concern
2001

Concerns About Antibacterial Household Products

publication Evidence: moderate

Author Information

Author(s): Stuart B. Levy

Primary Institution: Tufts University School of Medicine

Hypothesis

Do antibacterial household products contribute to antibiotic resistance?

Conclusion

The use of antibacterial products in healthy households may promote antibiotic resistance without providing any demonstrated health benefits.

Supporting Evidence

  • Antibacterial agents can select for resistant bacterial strains.
  • Triclosan resistance in E. coli mutants was linked to mutations in the fabI gene.
  • Community-acquired MRSA strains show different resistance profiles linked to antibacterial product use.
  • Excessive hygiene may interfere with normal immune system maturation.

Takeaway

Using antibacterial soaps and cleaners at home might make germs stronger and not help keep us healthy.

Methodology

Experiments were conducted to isolate resistant mutants of Escherichia coli and to study the effects of triclosan on bacterial growth.

Limitations

No current data demonstrate any health benefits from antibacterial products in healthy households.

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