Correlation Between SHBG and Blood Lipid and Glucose in Older Adults
Author Information
Author(s): Cao Meng, Jin Yaping, Yang Huili, Li Yuanbin, Liu Minhui, Huang Chongmei
Primary Institution: Ningxia Medical University
Hypothesis
To investigate the correlation between sex hormone binding globulin (SHBG) of serum lipid and blood glucose in middle-aged and older adults.
Conclusion
The study found that SHBG levels are negatively correlated with blood glucose levels in older women, while various lipid levels differ between genders.
Supporting Evidence
- The average levels of total cholesterol, HDL, LDL, and blood glucose were lower in men than in women.
- LDL-c and FBG levels increased with age in men, but SHBG levels decreased with age in women.
- There was a negative correlation between SHBG and FBG.
- Logistic regression analysis identified several risk factors for dyslipidemia.
Takeaway
This study looked at how a protein called SHBG relates to blood sugar and fat levels in older people, finding that it affects women differently than men.
Methodology
Participants were recruited from five urban communities using a cluster stratified sampling method, and data were analyzed using various statistical methods.
Participant Demographics
Participants were middle-aged and older adults (≥ 45 years old) from Ningxia province, with an average age of 63.53 years.
Statistical Information
P-Value
P=0.000, P=0.004, P< 0.05, P< 0.01
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website