Antibiotic-Impregnated Cement Spacer for Diabetic Osteomyelitis of the Foot
Author Information
Author(s): Khury Farouk, Karkabi Ihab, Mazzawi Elias, Norman Doron, Melamed Eyal A., Peled Eli, Anagnostakos Konstantinos
Primary Institution: Division of Orthopedic Surgery, Rambam Health Care Campus, Haifa, Israel
Hypothesis
What are the primary outcomes of diabetic osteomyelitis treated with antibiotic-impregnated cement spacer?
Conclusion
The antibiotic-impregnated cement spacer has shown excellent results in eradicating bone infection and preventing reoperation in diabetic osteomyelitis patients.
Supporting Evidence
- 52.72% of patients achieved primary successful infection eradication without further intervention.
- 89.18% of patients who achieved infection eradication did not undergo cement removal.
- Age and gender were positively correlated with reoperation rates.
Takeaway
This study looked at how a special type of cement that has antibiotics in it can help heal infections in the feet of people with diabetes. It found that most people got better without needing more surgery.
Methodology
The study was a retrospective review of 55 diabetic patients treated with antibiotic-impregnated cement spacer for osteomyelitis.
Potential Biases
Potential confounding factors were not captured due to the retrospective design.
Limitations
The study is limited by its retrospective nature and small sample size, and it did not include a control group.
Participant Demographics
36 males (65.45%) and 19 females (34.55%) with a median age of 64 years.
Statistical Information
P-Value
p=0.04 for age and gender correlation to reoperation.
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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