Link Between Cervical Cancer and HIV in Tanzania
Author Information
Author(s): Kahesa Crispin, Mwaiselage Julius, Wabinga Henry R, Ngoma Twalib, Kalyango Joan N, Karamagi Charles A S
Primary Institution: Ocean Road Cancer Research Institute
Hypothesis
Is there an association between invasive cancer of the cervix and HIV-1 infection in Tanzania?
Conclusion
HIV-1 infection is associated with invasive cancer of the cervix.
Supporting Evidence
- HIV-1 prevalence was higher among cases (21.0%) than controls (11.6%).
- The odds ratio for HIV-1 and cervical cancer was 2.9.
- Mean age of HIV-1 infected women with cervical cancer was lower than that of uninfected women.
Takeaway
Women with HIV are more likely to get cervical cancer, so we should help them get screened for it.
Methodology
A hospital-based case-control study with 138 cases and 138 controls was conducted to assess the association between HIV-1 and cervical cancer.
Potential Biases
Potential measurement bias and recall bias could have affected the results.
Limitations
Selection bias may have occurred as cases were selected from a single cancer treatment center.
Participant Demographics
Participants were women aged 18 and above, with a mean age of 50 years.
Statistical Information
P-Value
0.0001
Confidence Interval
95% CI = 1.4–5.9
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website