Regulation of phosphate homeostasis by the phosphatonins and other novel mediators
2008
Regulation of Phosphate Homeostasis by Phosphatonins
publication
Author Information
Author(s): Shaikh Aisha, Berndt Theresa, Kumar Rajiv
Primary Institution: Mayo Clinic Rochester
Hypothesis
Whether phosphatonins are true hormones regulated by dietary phosphorus intake remains to be established in humans.
Conclusion
Phosphatonins play a vital role in the pathogenesis of various disorders related to phosphate homeostasis.
Supporting Evidence
- Phosphatonins are identified as important regulators of phosphate homeostasis.
- Recent studies suggest that phosphatonins may mediate short-term changes in phosphate excretion after meals.
- Disorders like oncogenic osteomalacia and X-linked hypophosphatemic rickets are linked to phosphatonin activity.
Takeaway
Phosphatonins are special proteins that help control how our bodies use phosphorus, which is important for our bones and energy.
Digital Object Identifier (DOI)
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