Orthoplastic Approach to the Treatment and Reconstruction of a Neurotrophic Receptor Tyrosine Kinase Type 3 Soft Tissue Sarcoma Arising From the Occipitalis Muscle
2024

Orthoplastic Approach to Treating a Rare Soft Tissue Sarcoma

Sample size: 1 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Fiechter Jay G, Johnson Christopher, Bryant Justin, McCollom Joseph, Zhang Richard

Primary Institution: Indiana University School of Medicine, Fort Wayne, USA

Hypothesis

Can a multidisciplinary approach effectively treat a neurotrophic receptor tyrosine kinase type 3 soft tissue sarcoma arising from the occipitalis muscle?

Conclusion

The case demonstrates a successful treatment method for a low-grade soft tissue sarcoma using a multidisciplinary approach.

Supporting Evidence

  • This is the first case report showing an NTRK3 mutation STS arising from the occipitalis muscle.
  • Eighteen months after the procedure, no recurrent disease was detected.
  • The patient underwent R0 resection and staged reconstruction with hair-bearing tissue expansion.

Takeaway

Doctors worked together to help a woman with a rare tumor on her head, and they used special techniques to make her look normal again after surgery.

Methodology

The patient underwent R0 resection followed by staged hair-bearing tissue expansion for reconstruction.

Limitations

The study is based on a single case report with no randomized controlled trials available for this specific subtype.

Participant Demographics

A 40-year-old female patient.

Digital Object Identifier (DOI)

10.7759/cureus.74241

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