New, late-onset relapsing-remitting multiple sclerosis in a woman in her 60s after SARS-CoV-2 vaccination
2024

Late-Onset Multiple Sclerosis After COVID-19 Vaccination

Sample size: 1 publication Evidence: low

Author Information

Author(s): Scorza Carla Alexandra, Scorza Fulvio Alexandre, Finsterer Josef

Primary Institution: Universidade Federal de São Paulo (UNIFESP/EPM)

Hypothesis

Can SARS-CoV-2 vaccinations trigger new-onset multiple sclerosis in older adults?

Conclusion

This case suggests that SARS-CoV-2 vaccination may trigger the development of multiple sclerosis even in patients over sixty years of age.

Supporting Evidence

  • Multiple sclerosis was diagnosed after the patient met Mcdonald's criteria.
  • The patient had no prior symptoms of multiple sclerosis before vaccination.
  • Positive Oligoclonal Bands were found in the CSF examination.

Takeaway

A 67-year-old woman developed multiple sclerosis after getting COVID-19 vaccines, which is unusual for her age.

Methodology

The patient was diagnosed through clinical examination, MRI, and CSF analysis.

Potential Biases

Potential biases may arise from the lack of control group and reliance on patient self-reporting.

Limitations

The case is based on a single patient, making it difficult to generalize the findings.

Participant Demographics

67-year-old Caucasian woman.

Digital Object Identifier (DOI)

10.1016/j.clinsp.2024.100556

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