Wernicke's Encephalopathy in a Patient with Peptic Ulcer Disease
Author Information
Author(s): Uruha Akinori, Shimizu Toshio, Katoh Tomoji, Yamasaki Yasushi, Matsubara Shiro
Primary Institution: Tokyo Metropolitan Neurological Hospital
Hypothesis
Can peptic ulcer disease lead to Wernicke's encephalopathy due to thiamine deficiency?
Conclusion
The case suggests that peptic ulcer disease may provoke thiamine deficiency due to malabsorption, leading to Wernicke's encephalopathy.
Supporting Evidence
- The patient had a low thiamine concentration of 12.7 ng/mL.
- Neurological symptoms improved with thiamine administration.
- MRI showed typical findings associated with Wernicke's encephalopathy.
Takeaway
A 74-year-old man got a brain problem called Wernicke's encephalopathy because his stomach ulcers made it hard for his body to absorb a vitamin called thiamine.
Methodology
Case report detailing clinical presentation, diagnostic tests, and treatment response.
Limitations
The findings are based on a single case, limiting generalizability.
Participant Demographics
74-year-old male with a history of peptic ulcer disease.
Digital Object Identifier (DOI)
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