Genetic Linkage Map of the Prairie Vole Genome
Author Information
Author(s): Lisa A. McGraw, Jamie K. Davis, Larry J. Young, James W. Thomas
Primary Institution: Emory University
Hypothesis
What is the genetic linkage map of the prairie vole genome and how does it compare to other rodent genomes?
Conclusion
The study successfully constructed a genetic linkage map of the prairie vole, which will aid in understanding social behaviors and genome evolution in this species.
Supporting Evidence
- The linkage map consists of 406 markers spaced every 7 Mb, covering ~90% of the prairie vole genome.
- The prairie vole linkage map is the fourth genome-wide high-resolution linkage map for Muroid rodents.
- Comparative analyses revealed 61 blocks of conserved synteny with the mouse genome.
Takeaway
Scientists made a map of the prairie vole's genes to help understand how they behave and how their genes have changed over time.
Methodology
The study involved genotyping SNPs in a panel of prairie voles and constructing a linkage map based on the genotypes.
Limitations
The linkage map may contain errors regarding the true marker order in the genome.
Participant Demographics
The study involved 353 prairie voles from a local breeding colony.
Statistical Information
P-Value
p < 0.0003
Statistical Significance
p < 0.012
Digital Object Identifier (DOI)
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