Standardized Nutrition for Very Preterm Infants
Author Information
Author(s): Morgan Colin, Herwitker Shakeel, Badhawi Isam, Hart Anna, Tan Maw, Mayes Kelly, Newland Paul, Turner Mark A
Primary Institution: Liverpool Women's Hospital
Hypothesis
We speculate that the scNPN and scNPNmax regimens will provide efficient macronutrient delivery in the early neonatal period.
Conclusion
Optimizing early protein and energy intake could improve head growth in very preterm infants.
Supporting Evidence
- Infants <29 weeks gestation are at high risk of neurocognitive disability.
- Optimal protein and calorie intakes are rarely achieved in the first week.
- Standardised PN solutions can improve macronutrient intake.
Takeaway
This study is trying to find out if giving more nutrients to very small babies can help them grow better in their first month.
Methodology
A single centre, parallel group, randomised controlled trial comparing two neonatal parenteral nutrition regimens.
Potential Biases
Potential bias in nutritional delivery due to individualised prescription practices.
Limitations
No randomised controlled trials comparing standardised versus individualised neonatal PN have been conducted due to logistical challenges.
Participant Demographics
Infants born 24-28 weeks gestation and weighing less than 1200 g.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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