Factors Affecting Blood Flow Resistance in Diabetic Kidney Patients
Author Information
Author(s): Anubhav Thukral, Manish Mishra, Vaibhava Srivastava, Hemant Kumar, Amit Nandan Dwivedi, Ram Chandra Shukla, Kamlakar Tripathi
Primary Institution: Institute of Medical Sciences, Banaras Hindu University
Hypothesis
Can renal vascular resistance be correlated with various clinical factors in diabetic nephropathy patients?
Conclusion
Renal vascular resistance may help identify diabetics at high risk of developing nephropathy.
Supporting Evidence
- Renal vascular resistance correlated with age, duration of disease, GFR, serum creatinine, and stage of retinopathy.
- Patients on RAAS inhibitors and insulin had significantly lower renal vascular resistance compared to those on other treatments.
- RI values started increasing in diabetic subjects even before the appearance of microalbuminuria.
Takeaway
This study looked at how blood flow resistance in the kidneys can help doctors find out which diabetes patients might get kidney problems.
Methodology
Renal vascular resistance was measured using noninvasive color Doppler examinations in diabetic nephropathy patients and compared with controls.
Potential Biases
Potential bias due to the hospital-based sample and exclusion of patients with certain conditions.
Limitations
The study had a small sample size and was cross-sectional in nature.
Participant Demographics
All participants were type 2 diabetes patients, with a mix of diabetic nephropathy and control subjects.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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