Cell therapies for viral diseases: a new frontier

publication Evidence: moderate

Author Information

Author(s): Nardo David, Maddox Emileigh G., Riley James L.

Primary Institution: University of Pennsylvania

Can cellular therapies improve patient outcomes in viral infections?

Cellular immunotherapy may offer effective solutions to combat viral infections by enhancing immune responses.

Cellular therapies have shown promise in treating viral infections that currently lack effective treatments.
Virus-specific T cell therapy has been successful in preventing infections in bone marrow transplant recipients.
Recent trials indicate that multi-virus therapies can induce immune responses against multiple pathogens.

Scientists are exploring new ways to use immune cells to fight viruses, which could help people who get sick from infections like HIV.

The review summarizes findings on various cellular therapies, including virus-specific T cells, CAR T cells, and mesenchymal stem cells.

The variability in clinical trials makes it difficult to assess the effects of therapies for individual infections.

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