Prognostic factors in patients with gastrointestinal perforation under the acute care surgery model: a retrospective cohort study
2024

Prognostic Factors in Patients with Gastrointestinal Perforation

Sample size: 354 publication 10 minutes Evidence: moderate

Author Information

Author(s): Sung Kiyoung, Hwang Sanguk, Lee Jaeheon, Cho Jinbeom

Primary Institution: Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea

Hypothesis

This study aims to identify prognostic factors in patients with gastrointestinal perforation treated within a standardized acute care surgery framework.

Conclusion

Establishing a system for rapid preoperative work-up and evidence-based postoperative care could improve patient outcomes in gastrointestinal perforation cases.

Supporting Evidence

  • Mortality was 11%, and 38% of survivors experienced significant complications.
  • Independent prognostic factors for mortality included initial SOFA scores and postoperative body temperatures.
  • Patients with specific p-SOFA scores and albumin levels had a 100% mortality rate.

Takeaway

Doctors studied patients with a serious stomach problem to find out what factors help predict who will get better or worse after surgery.

Methodology

This was a single center retrospective cohort study analyzing patients diagnosed with gastrointestinal perforation who underwent emergent surgery and were admitted to the ICU from January 2013 to March 2023.

Potential Biases

The study's retrospective nature may introduce biases related to data collection and patient selection.

Limitations

The cohort was not large enough to accurately calculate cut-off values, and there were issues with data distribution and missing data.

Participant Demographics

Patients aged 18 and older diagnosed with gastrointestinal perforation.

Statistical Information

P-Value

p<0.05

Confidence Interval

(1.10, 1.88)

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/s12893-024-02687-7

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