A reversible lesion of the corpus callosum splenium with adult influenza-associated encephalitis/encephalopathy: a case report
2008

Reversible Lesion of the Corpus Callosum in Adult Influenza Encephalitis

Sample size: 1 publication Evidence: low

Author Information

Author(s): Kimura En, Okamoto Sadahisa, Uchida Yuji, Hirahara Tomoo, Ikeda Tokunori, Hirano Teruyuki, Uchino Makoto

Primary Institution: Department of Neurology, Graduate School of Medical Sciences, Kumamoto University

Hypothesis

Can adults experience reversible lesions in the corpus callosum due to influenza-associated encephalitis?

Conclusion

Adult patients can experience reversible lesions in the corpus callosum associated with influenza, which may recover quickly.

Supporting Evidence

  • The patient had a high fever and neurological symptoms after influenza infection.
  • Initial MRI showed lesions in the corpus callosum that resolved by day 8.
  • Cytokine levels were elevated initially but returned to normal after treatment.

Takeaway

A 35-year-old man got very sick from the flu and had some brain problems, but he got better quickly after treatment.

Methodology

The patient was treated with oseltamivir and methylprednisolone, and MRI scans were used to monitor brain lesions.

Limitations

Only one case is reported, limiting generalizability.

Participant Demographics

One previously healthy 35-year-old male.

Digital Object Identifier (DOI)

10.1186/1752-1947-2-220

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