Metastatic Disease to the Breast: A Study from Washington University
Author Information
Author(s): Vaughan Aislinn, Dietz Jill R, Moley Jeffrey F, DeBenedetti Mary K, Aft Rebecca L, Gillanders William E, Eberlein Timothy J, Ritter Jon, Margenthaler Julie A
Primary Institution: Washington University School of Medicine
Hypothesis
The study aims to characterize metastatic disease to the breast and describe the management and prognosis of patients with this diagnosis.
Conclusion
A multi-disciplinary approach is necessary for patients with metastatic disease to the breast, as many can survive for long periods with appropriate local treatment.
Supporting Evidence
- Eighteen patients with metastatic disease to the breast were identified between 1991 and 2006.
- The overall mean survival after diagnosis of metastatic disease to the breast was 22.4 months.
- Five patients (27.8%) required a change in management for local control of their breast disease.
Takeaway
This study looked at patients who had cancer spread to their breasts from other parts of the body. It found that with the right treatment, some patients can live a long time even with this serious condition.
Methodology
A retrospective review of pathology and breast cancer databases was performed to identify patients with breast malignancies that were not of primary breast origin.
Limitations
The study is limited by its retrospective nature, small sample size, and variability in treatment methods.
Participant Demographics
The study included 18 patients with various primary malignancies, predominantly women.
Digital Object Identifier (DOI)
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