Cervical masses as manifestation of papillary thyroid carcinomas ≤10 mm in diameter, in patients with unknown thyroid disease
2008

Cervical masses and small papillary thyroid carcinomas

Sample size: 54 publication 10 minutes Evidence: moderate

Author Information

Author(s): Pazaitou-Panayiotou Kalliopi, Alevizaki Maria, Boudina Maria, Drimonitis Apostolos, Kiziridou Anastasia, Vainas Iraklis

Primary Institution: Theagenion Cancer Hospital, Thessaloniki, Greece

Hypothesis

Are cervical masses indicative of papillary thyroid carcinomas that are 10 mm or smaller in patients with unknown thyroid disease?

Conclusion

Papillary thyroid microcarcinomas can exhibit aggressive behavior and may present with cervical metastases, necessitating careful treatment and follow-up.

Supporting Evidence

  • Patients with cervical masses had a higher incidence of lymph node metastases compared to those with nodular goiter.
  • All patients in the cervical mass group had multifocal papillary thyroid carcinomas.
  • Follow-up showed that some patients developed new cervical metastases after initial treatment.

Takeaway

Some small thyroid tumors can be sneaky and cause problems even if they are tiny, so doctors need to keep a close eye on them.

Methodology

Patients with cervical masses were compared to those with nodular goiter to assess the presence of papillary thyroid microcarcinomas.

Potential Biases

Potential selection bias due to the retrospective nature of the study.

Limitations

The study is retrospective and may not account for all variables affecting outcomes.

Participant Demographics

54 patients, including 46 women and 8 men, aged 16-70 years.

Statistical Information

P-Value

0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1756-6614-1-8

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